Key Ingredients to Actively Benefit Your Brain | Marbles

Neuro-phytoactives

Marbles is a powerful formulation of plant-based molecules to actively benefit your brain.

Developed from leading research into the protective properties of plant-based molecules,
Marbles contain a proprietary blend of Citrus bioflavonoids and extracts from Matricaria chamomilla flower and Theobroma cacao bean.

Citrus bioflavonoids

It is well known that the frequent consumption of citrus fruits that include orange, mandarin, lemon and lime, can support long-term health and wellbeing. Citrus, one of the most sought-after fruit crops, provides a rich source of antioxidants and contains a host of neuro-phytoactives to maintain brain function and reduce inflammation.

  • Anti-inflammatory 10
  • Supports cognition and mental function 10
  • Maintains brain health 10
  • Antioxidant  ²
  • Helps maintain concentration and focus 10
  • Reduces cell damage caused by free radicals 22

Matricaria chamomilla

Chamomile is one of the most ancient medicinal plant species known to mankind. Nowadays it is highly favoured through years of traditional use and scientific research. The phytoactive compounds of this plant offer potential for relieving inflammation, in turn supporting long-term brain health.

Theobroma cacao

It is a popular belief that eating chocolate can support a healthy mood and promote feelings of wellbeing. Cacao is a rich source of neuro-phytoactives with beneficial effects on cerebral blood flow to support energy levels and various aspects of cognition.

  • Anti-inflammatory 1, 23
  • Supports cognition and mental function 4, 5, 9, 10, 15
  • Supports energy levels and vitality 8, 9, 14, 15
  • Antioxidant 1, 3, 14
  • Supports healthy emotional mood and balance 14, 15
  • Supports healthy sleep patterns 7
  • Maintains brain health and mental wellbeing 4, 14, 15
  • Helps maintain concentration and focus 4
  • Reduces cell damage caused by free radicals 1, 3

Access the benefits of phytoactives with Marbles.

Evidence suggests that the neuro-phytoactives found in Marbles have a fundamental influence on many aspects of brain health including energy, resilience, cognitive processes and emotions.

Sources of  evidence

1. Latif, R. (2013), Chocolate/cocoa and human health: a review, Netherlands Journal of Medicine, Vol 71, No.2, 63-68.

2. Rafiq, S., Kaul, R., Sofi, S.A., Bashir, N., Nazir, F. & Nayik, G.A. (2016), Citrus peel as a source of functional ingredient: a review, Journal of the Saudi Society of Agricultural Sciences, 1-8.

3. Cooper, K.A., Donovan, J.L., Waterhouse, A.L.& Williamson, G. (2008), Cocoa and health: a decade of research, British Journal of Nutrition, Vol. 99, 1-11.

4. Scholey, A. & Owen, L. (2016), Effects of chocolate on cognitive function and mood: a systematic review, Nutrition Reviews, 665-681.

5. Nehlig, A. (2012), The neuroprotective effects of cocoa flavanol and its influence on cognitive performance, British Journal of Clinical Pharmacology, 716-727.

6. Adib-Hajbaghery, M & Mousavi, S.N. (2017), The effects of Chamomile extract on sleep quality among elderly people: A clinical trial, Complementary Therapies in Medicine, 109-144.

7. Michael A. Grandner, Nicholas Jackson, Jason R. Gerstner, Kristen L. Knutson. (2013), Dietary nutrients associated with short and long sleep duration, Appetite Journal, 71-80.

8. David L. Katz, Kim Doughty, and Ather Ali. (2011), Cocoa and chocolate in human health and disease, Antioxidants & Redox Signalling, Volume 15, Number 10, 2779-2811.

9. Grassi D, Socci V, Tempesta D, Ferri C, De Gennaro L, Desideri G,et al. (2016), Flavanol-rich chocolate acutely improves arterial function and working memory performance counteracting the effects of sleep deprivation in healthy individuals, Journal of Hypertension 34(7), 1298-1308.

10. Spencer, J. (2009), Flavonoids and brain health: multiple effects underpinned by common mechanisms, Genes and Nutrition Publisher BioMed Central, 243-250.

11. Natural Health Product Directorate (2018), Single Ingredient Monographs: German Chamomile – Matricaria Chamomilla Health Canada, Natural Health Products Ingredients Database.

12. Bisset, N.G. & Wichtl, M. (2001), Herbal Drugs and Phytopharmaceuticals: A Handbook for Practice on a Scientific Basis (2nded), Stuttgard: Medpharm, CRC Press.

13. European Medicines Agency (2015), European Union Herbal Monograph: Matricia Flower, Matricia recutita L, flos. European Union, Committee on Herbal Medicinal Products.

14. Braun, L. & Cohen, M. (2015), Herbs and Natural Supplements: An Evidence-based Guide (4thed), Chatswood, N.S.W.: Churchill Livingstone/Elsevier.

15. Leah Hechtman. (2012), Clinical Naturopathic Medicine, Chatswood, N.S.W.: Churchill Livingstone/Elsevier.

16. Gruenwald, J., Brendler, T. & Jaenicke, C. (2000), PDR for Herbal Medicines (2nded), Medical Economics Co.: Montvale, NJ.

17. Bone, K & Mills, S. (2013), Principles and Practice of Phytotherapy: Modern Herbal Medicine (2nded), London, UK: Churchill Livingstone/Elsevier.

18. Barnes, J., Anderson, L. & Phillipson, D. (2007), Herbal Medicines, United Kingdom: Pharmaceutical Press.

19. Blumenthal, M et al. (1998), The Complete German Commission E Monographs, Single Ingredient Monographs – Matricaria Chamomilla, Austin, Texas: Boston: American Botanical Council.

20. European Scientific Cooperative on Phytotherapy. (2003), E/S/C/O/P monographs: The scientific foundation for herbal medicinal products, Single Ingredient Monographs – Matricariae flos, Exeter, Great Britain: ESCOP.

21. World Health Organization. (1999), WHO Monographs on Selected Medicinal Plants (Vol1), Single Ingredient Monograph – Flos Chamomillae, World Health Organization, Geneva

22. Drugs and Health Products (2015), Antioxidants – Citrus Bioflavonoids, Health Canada, Natural Health Products Ingredients Database.

23. Becker, K., Geisler, S., Ueberall, F., Fuchs, D., & Gostner, J. M. (2013), Immunomodulatory properties of cacao extracts – potential consequences for medical applications. Frontiers in pharmacology4, 154.

24. Srivastava, J. K., Shankar, E., & Gupta, S. (2010), Chamomile: A herbal medicine of the past with bright future. Molecular medicine reports3(6), 895–901.

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